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KMID : 0545120000100050733
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Journal of Microbiology and Biotechnology
2000 Volume.10 No. 5 p.733 ~ p.736
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Comparison of the Solution Structure of Vancomycin with Its X-ray Crystallographic Structure
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LEE, CHUL-HOON
kYUNG, HANSOO/LIM, YOONGHO
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Abstract
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Since pathogens resistant against vancomycin occur rapidly, the development of a new drug is needed. To make a new drug based on a rational drug design, the structural study of vancomycin is necessary. Accordingly, this study reports on a comparison of the solution structure of vancomycin determined by NMR spectroscopy, which was performed in the present work, with the X-ray crystallographic structure previously deposited in the Protein Data Bank (PDB).
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